Bill said it the best here:
David makes some excellent points. The 5.7s internals (rotating assembly) are "cast" not "forged" and therefore cannot take the same stresses. As I understand it, with the right tune, you can safely run forced induction on a stock 5.7 as long as you keep the boost at or under 6-7 psi. ....
... Expect to gain up to 100 hp*** (I think actually around 130rwhp ) with a supercharger and no other internal modification. There is no way to achieve 600 hp on a 5.7 with stock internals and have it last.
A Diablosport Predator or Trinity would cover the tuning chores. (most supercharger kits come with one and you can get a base tune) Keep in mind that a CMR tune (preferably dyno tuning) would be required to achieve the most power without grenading your motor. (Exactly!!! you need to have a custom tune done after install!!!)
You get what you pay for when it comes to the kits in my opinon. It has been shown that if you just stick with the base supercharger kits, your stock bottom will be fine and without sacrificing much longevity of the motor. I know guys that have turned over 60,000 miles with their blower and have had zero issues. Transmission will hold up just fine being stock with a base supercharger kit. The only thing you may have to upgrade is your half shafts; Stock motors have broken half shafts! The key here is the guys had been running slicks. So if you don't want to upgrade your half shafts, then run the stock tires only and don't do any high stall launches and you will be fine.
So IMO if you spend some good coin on a reputable company and stick with their base kit, you should be ok
-429ci stroker,techco twinscrew
-Snow Performance Stage 2 Boost Cooler
-Autozone 170 degree T-stat
-Diablo Predator Tuner
-World's Fastest Magnum 195.3mph!!!